Transperineal MRI–Guided Prostate Biopsy

Transperineal MR Imaging–Guided Prostate Biopsy: A Prospective Randomized Controlled Study on Safety and Effectiveness Compared with Transrectal Biopsy

🔍 **Clinical Question:** 

Is magnetic resonance (MR) imaging–guided in-bore transperineal prostate biopsies (TP-Bx) safe and tolerable?

💡 **Key Insight:** 

Adverse events occurred in 8.9% of patients undergoing transrectal prostate biopsy and 4.4% of patients undergoing transperineal prostate biopsy, with no significant difference between groups. Transperineal approach demonstrated a higher cancer detection rate (42.5%) than transrectal approach (28.2%) and a significantly higher clinically significant cancer detection rate (27.5% vs 7.7%, P = .019). 

Quality-of-life and pain assessments showed no significant differences between groups, although changes in management were more frequent following transperineal prostate biopsy (32.5% vs 15.4%, P = .050).

👉 **Why it matters:** 

MR imaging–guided transperineal prostate biopsy is a safe and effective procedure with an enhanced detection rate in non–biopsy-naïve patients, with significant impact on clinical management strategies.

➡️ **Full Article:**

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#InterventionalRadiology #IO #Biopsy #MedEd

Post author

Annie Phan

MS4 Medical Student

University of Massachusetts Chan Medical School