PAVM Transarterial Embolization - Meta Analysis

Transarterial Embolization for Pulmonary Arteriovenous Malformation: A Systematic Review and Meta-Analysis 

🔍 **Clinical Question:** 

Does an updated meta-analysis continue to show that transcatheter embolization for treatment of pulmonary arteriovenous malformations (PAVMs) is safe and effective? What additional insights does it offer? 

💡 **Key Insight:** 

Transcatheter embolization for pulmonary arteriovenous malformations demonstrated a high technical success rate (>98%), whereas the reported rate of postembolization catastrophic events was low (1.0%). The use of vascular plugs was associated with significantly lower persistence rates than coils only (13.6% vs 32.7%). 

Venous sac embolization showed a markedly lower persistence rate than feeding artery embolization (3.8% vs 24.3%). 

👉 **Why it matters:** 

PAVM embolization, especially using vascular plugs and encompassing venous sac embolization, has favorable technical and treatment success rates and low risk of severe AEs. 

➡️ **Full Article:** 

brnw.ch... 

#InterventionalRadiology #pAVM #HHT #Meta-Analysis #MedEd

Transperineal MRI–Guided Prostate Biopsy

Transperineal MR Imaging–Guided Prostate Biopsy: A Prospective Randomized Controlled Study on Safety and Effectiveness Compared with Transrectal Biopsy

🔍 **Clinical Question:** 

Is magnetic resonance (MR) imaging–guided in-bore transperineal prostate biopsies (TP-Bx) safe and tolerable?

💡 **Key Insight:** 

Adverse events occurred in 8.9% of patients undergoing transrectal prostate biopsy and 4.4% of patients undergoing transperineal prostate biopsy, with no significant difference between groups. Transperineal approach demonstrated a higher cancer detection rate (42.5%) than transrectal approach (28.2%) and a significantly higher clinically significant cancer detection rate (27.5% vs 7.7%, P = .019). 

Quality-of-life and pain assessments showed no significant differences between groups, although changes in management were more frequent following transperineal prostate biopsy (32.5% vs 15.4%, P = .050).

👉 **Why it matters:** 

MR imaging–guided transperineal prostate biopsy is a safe and effective procedure with an enhanced detection rate in non–biopsy-naïve patients, with significant impact on clinical management strategies.

➡️ **Full Article:**

brnw.ch... 

#InterventionalRadiology #IO #Biopsy #MedEd

Post author

Annie Phan

MS4 Medical Student

University of Massachusetts Chan Medical School