Monday, January 12, 2026

TAME for Chronic Toe Pain

 Transarterial Microembolization Therapy for Chronic First Metatarsophalangeal Joint Pain



🔍 **Clinical Question:**  

To evaluate the feasibility, safety, and preliminary effectiveness of transarterial microembolization (TAME) for refractory first metatarsophalangeal joint (MTPJ) pain in patients with inflammatory arthritis, gout, or osteoarthritis.


💡 **Key Insight:**  

Transarterial microembolization (TAME) targets hypervascularity and pathological nerve ingrowth, key contributors to chronic pain, by selectively embolizing feeder arteries, thereby disrupting pain pathways and reducing inflammatory mediators.

TAME demonstrated significant reduction in pain and weekly analgesic use, establishing it as a safe and effective minimally invasive alternative for managing chronic metatarsophalangeal joint pain refractory to conventional treatments.


👉 **Why it matters:**  

The favorable safety profile and effectiveness of TAME suggest potential applications in other small joint pathologies.


➡️ **Full Article:** 

https://doi.org/10.1016/j.jvir.2025.08.047


#InterventionalRadiology #MSKIR #Pain #OA #MedEd

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