RFA for Multinodular Goiter

Radiofrequency Ablation in the Management of Extensive Multinodular Goiter: A Midterm Single-Center Experience

🔍 **Clinical Question:**

Is radiofrequency (RF) ablation effective in providing cosmetic and symptom relief for patients with extensive multinodular goiter?

💡 **Key Insight:**

This study evaluated the effectiveness of radiofrequency (RF) ablation in patients with extensive multinodular goiter, targeting at least 3 nodules in bilobar distribution with a follow-up of 40.5 months.

RF ablation demonstrated a mean volume reduction of 85.3% in treated thyroid nodules, significantly improving both cosmetic appearance and local symptoms.

Repeated RF ablation sessions were required in 32.5% of patients due to additional target nodules, incomplete ablation, or new nodule growth.

👉 **Why it matters:**

Radiofrequency (RF) ablation in patients with extensive multinodular goiter avoids the need for thyroid hormone replacement therapy or surgery and provides a rate of cosmetic and symptom relief comparable with that achieved by RF ablation in cases of uninodular or binodular goiter.

➡️ **Full Article:** 

https://doi.org/10.1016/j.jvir.2025.06.020

#InterventionalRadiology #IO #Ablation #RFA #Goiter #Thyroid #MedEd

GAE with Mesenchymal Stem Cells for OA

Genicular Artery Embolization Using Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Prospective Study

🔍 **Clinical Question:**

Is genicular artery embolization (GAE) using mesenchymal stem cells safe and feasible in patients with bilateral knee osteoarthritis (OA)?

💡 **Key Insight:**

Mesenchymal stem cells were safely delivered via genicular arteries (GAE) to subjects with Kellgren-Lawrence Stage 3 knee osteoarthritis (OA). During a 12-month follow-up period, there were no study-related adverse events.

There were significant improvements in objective pain, stiffness, and function compared with the contralateral control knee.

👉 **Why it matters:**

Direct delivery of stem cells via genicular artery embolization (GAE) by interventional radiology (IR) may represent a new avenue for treatment in patients with osteoarthritis (OA).

➡️ **Full Article:** 

https://doi.org/10.1016/j.jvir.2025.05.031

#InterventionalRadiology #MSKIR #GAE #OA #MedEd