GAE with Mesenchymal Stem Cells for OA

Genicular Artery Embolization Using Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Prospective Study

🔍 **Clinical Question:**

Is genicular artery embolization (GAE) using mesenchymal stem cells safe and feasible in patients with bilateral knee osteoarthritis (OA)?

💡 **Key Insight:**

Mesenchymal stem cells were safely delivered via genicular arteries (GAE) to subjects with Kellgren-Lawrence Stage 3 knee osteoarthritis (OA). During a 12-month follow-up period, there were no study-related adverse events.

There were significant improvements in objective pain, stiffness, and function compared with the contralateral control knee.

👉 **Why it matters:**

Direct delivery of stem cells via genicular artery embolization (GAE) by interventional radiology (IR) may represent a new avenue for treatment in patients with osteoarthritis (OA).

➡️ **Full Article:** 

https://doi.org/10.1016/j.jvir.2025.05.031

#InterventionalRadiology #MSKIR #GAE #OA #MedEd